Antioxidant Role of PRGF on RPE Cells after Blue Light Insult as a Therapy for Neurodegenerative Diseases
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چکیده
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assessment of the effect of honey as a topical therapy for intra oral wound healing in rat.
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15 صفحه اولOn The Role of Natural Killer Cells in Neurodegenerative Diseases
Natural killer (NK) cells exert important immunoregulatory functions by releasing several inflammatory molecules, such as IFN-γ and members of chemokines, which include CCL3/MIP-1α and CCL4/MIP-1β. These cells also express heptahelical receptors, which are coupled to heterotrimeric G proteins that guide them into inflamed and injured tissues. NK cells have been shown to recognize and destroy tr...
متن کاملThe influence of sublethal blue light exposure on human RPE cells
PURPOSE To evaluate the in vitro response of retinal pigment epithelial (RPE) cells to a nonlethal dose of blue light. METHODS The human RPE cell line ARPE-19 was irradiated with blue light (405 nm) at an output power of 1 mW/cm(2) or 0.3 mW/cm(2). The following parameters were studied: metabolic activity; apoptosis; reactive oxygen species (ROS) production; mitochondrial membrane potential (...
متن کاملStem Cell Therapy for Neurodegenerative Diseases
002 drugs against AD [7]. Bone marrow-derived mesenchymal stem cells (MSCs) were able to home on the injured brain and remove Abeta plaques from the hippocampus and to reduce Abeta deposits through the activation of endogenous microglia in an induced AD mouse model [8]. Human umbilical cord-derived MSCs have been shown to improve memory deficits, and reduce Abeta deposition [9]. Moreover, one r...
متن کاملStem Cell Therapy for Neurodegenerative Diseases
Neurodegenerative diseases, amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD), Parkinson’s disease (PD), frontotemporal lobar degeneration (FTLD), Huntington’s disease (HD), and multiple sclerosis (MS), are characterized by progressive degeneration of particular neuronal cells. Neurodegenerative disorders are believed to share a common pathophysiologic mechanism that allows the depo...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2020
ISSN: 1422-0067
DOI: 10.3390/ijms21031021